(Berlin, October 2017) The 5th BioProScale Symposium “Innovative scale up and scale down for bioprocess intensification” takes place from 20 to 22 March 2018 in Berlin, Germany. The symposium is targeted at experts from research & development and industrial practice from producers of biogas and enzymes, antibiotic production, bioprocess development, pharmaceutical bioprocesses and food processes.
Consistent bioprocess development needs to be performed at the perspective of the final process scale. As a result a better understanding of the final industrial scale is indispensable. This includes technical challenges (sensors, modelling tools) and the cellular dynamic regulatory networks and population dynamics.
“Our aim is to bring stakeholders which work with different large-scale bioprocesses together in order to discuss their experiences and research needs” says Prof. Dr. Peter Neubauer, Head of the Chair of Bioprocess Technology of Technische Universität Berlin and organiser of the symposium.
The symposium topics include in particular:
Industrial-scale bioprocess operation
Manufacturing at large scale from process to product, modelling of large scale processes, mixing and reactor characterization, scaleability of operations, process robustness and repeatability, process monitoring and advanced control, integrated upstream and downstream operations, population heterogeneity
Process analytical technologies (PAT) for understanding bioprocess scale up
Multiparameter analysis, non-invasive sensors, single-cell based monitoring, soft sensors, fault identification and diagnosis, multiposition measurements, mechanistic modelling and scale effects
Bioprocess development and intensification
Automated screenings for biomolecules and bioprocess development, computer aided operations, optimal experimental design, miniaturisation of bioprocesses, operational space characterisation, evolutionary strategies for strains and processes
Single use processes
Reactor types from µl to m³, sensors for single use processes, scalability, sustainability, continuous processing, microbial and niche applications
Scaling of bioprocesses for the circular economy
Waste streams to value-added products, pretreatment, feedstock flexibility, scale up/down of biorefinery concepts, closed carbon cycles, smart bioproduction grids
Microsensors for bioprocesses
Miniaturisation through microelectronics, physical sensors, biosensors, intelligent microtiter plates, co-integration of microfluidics, lab-on-chip systems
The 5th BioProScale Symposium is jointly organised by the Technische Universität Berlin, Chair of Bioprocess Technology, and the Institute for Gaerungsgewerbe und Biotechnologie zu Berlin (IfGB). Congress language is English. More information and registration at www.bioproscale-conference.org.