5th BioProScale Symposium 2018

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Tuesday Wednesday Thursday

Thursday, March 22, 2018

Historical Lecture Hall (2nd Floor)

9:00 Industrial scale process optimization for manufacturing of scFv-class antibody (L55)
Guido Seidel, Wacker Biotech GmbH, Jena, Germany
9:45 Short break  
Session 7A: Process Analytical Technologies
Chair: Alain Sourabié / Anika Bockisch  
9:55 Keynote talk: Controlling microbial population at a single cell resolution: from cybergenetics to bioprocess engineering (L56)
Frank Delvigne, University of Liège, Belgium
10:25 Budding index, a real-time parameter for monitoring (L57)
Anna Maria Marbà Ardébol, TU Berlin, Germany
10:45 In-line determination of spectral light distribution and biomass production in photobioreactors by fibre-optical methods: Spatially distributed light sensing and photon density wave spectroscopy (L58)
Stephanie Schönfelder, University of Potsdam. Germany
11:05 Coffee break, poster session and exhibition  
Session 8A: Process Analytical Technologies
Chair: Peter Götz / Anna Maria Marbà-Ardébol  
11:55 Tandem talk: Laser-based in situ back reflection analysis of particle sizes during feedstock pre-treatment by multi capture signal interpretation (L62)
Stefan Junne, TU Berlin, Germany & Herrmann B. Schwartz, Sequip GmbH Düsseldorf, Germany
12:20 Comparison of vibrational spectroscopic techniques for PAT in industrial biotechnology (L63)
Edo Becker, Keit Spectrometers
12:40 In situ Raman spectroscopy as a promising PAT tool for monitoring of macro and micro-heterogeneity of antibody glycosylation (L64)
Meng-Yao Li, LRGP, France
13:00 SERS and Time-Gated (TG-SERS) Raman spectroscopy as advanced PAT tools for monitoring of lactic acid bacteria fermentations (L65)
Martin Kögler, VTT, Oulu, Finland
13:20 Lunch break, poster session and exhibition
Session 9A: Bioprocess Development  
Chair: Frank Delvigne / Matthias Gimpel
14:20 Keynote talk: Taking the microbial perspective: computational fluid dynamics for bioprocesses design, operation and optimization (L70)
Cees Haringa, DSM Biotechnology Center, Delft, The Netherlands
14:50 CFD-based strategy to optimize the impeller design for mesenchymal stem cells cultures in bioreactors (L71)
Céline Loubière, Université de Lorraine, Metz, France
15:10 CHO cell-free protein synthesis for mammalian protein production and future bioprocess development (L72)
Lena Thoring, Fraunhofer IZI-BB, Potsdam, Germany
15:30 Reactors for electrobiotechnology: Upgrading bioreactors for bioelectrosynthesis (L73)
Luis Rosa, Helmholtz Zentrum für Umweltforschung, Germany
15:50 Keynote talk: Opportunities and challenges of model-based control of pellet growth in industrial-scale penicillin fermentation (L74)
Timo Hardiman, Sandoz, Kundl, Austria
16:20 Closing remarks
Peter Neubauer, TU Berlin
16:30 End of conference


Bernhard von Langenbeck Hall (1st floor)

Session 7B: Automated Bioprocess Development
Chair: Krist V. Gernaey, M. Nicolas Cruz B.
9:55 Multi-feed simultaneous saccharification and fermentation: model-based development of high gravity lignocellulose-based bioprocesses (L59)
Carl Johan Franzén, Chalmers University of Technology, Sweden
10:25 Entering the next dimension: microfluidic single-cell analysis of bacterial interaction (L60)
Alina Burmeister, Forschungszentrum Jülich, Germany
10:45 Using integrated process modelling towards understanding process variation across unit operations (L61)
Christopher Taylor, Exputec GmbH, Vienna, Austria
11:05 Coffee break and poster session and exhibition
Session 8B: Automated Bioprocess Development
Chair: Carl Johan Franzén / Florian Glauche
11:50 Keynote talk: Beyond miniaturization and parallelization: standard and tailor-made automated workflows for smart microbial bioprocessing (L66)
Marco Oldiges, Forschungszentrum Jülich, Germany
12:20 Model based design of experiments for high throughput bioprocess development (L67)
Mariano Nicolas Cruz Bournazou, TU Berlin, Germany
12:40 Mastering the digital transformation challenge in biopharmaceutical processing (L68)
Michael Sokolov, ETH Zürich, Switzerland
13:00 From automated genetic element screening to automated early stage bioprocess development in miniaturized stirred-tank reactors (L69)
Nils Janzen, Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria
13:20 Lunch break, poster session and exhibition
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