10:00

Welcome addresses and introduction

Peter Neubauer, TU Berlin, Germany

10:20

Plenary Talk: Zero concepts in bioprocessing: towards the ultimate performance

Henk Norman, DSM, The Netherlands

11:35

Digital twins for improved bioprocess operation?

Krist V. Gernaey, Technical University of Denmark, Denmark

12:05

Towards increased stability in large-scale bioreactors by bacterial co-cultures

Pauli Losoi, Tampere University, Finland

12:25

Dynamic genome scale modeling of Streptomyces clavuligerus metabolism for studying ist metabolic performance under different shear stress conditions

David Gómez-Rios, Universidad de Antioquia, Colombia

11:35

Interfacing single cell technologies for stabilizing microbial cell population in continuos cultivation

Frank Delvigne, Université de Liège, Belgium

12:05

Continuous E. coli bioprocessing: Monitoring of subpopulations and how to deal with them

Julian Kopp, TU Wien, Austria

12:25

What is beyond the average - a step toward quantifying the specific reactivity of single cells?

Martin Schirmer, University Leipzig, Germany

14:30

New experimental methods for detecting heterogeneous flow structures in bioreactors pave the way for a more reliable scale-down and scale-up

Michael Schlüter, TU Hamburg, Germany

15:00

CFD-based dynamic compartment modelling for the time-series prediction of gradients in industrial-scale aerobic fed-batch fermentation processes

Gisela Nadal Rey, Technical University of Denmark, Denmark

15:20

Heat balance and CFD coupling strategy for the scale-up of an innovative bioleaching process

Céline Loubiere, Bureau de Recherches Géologiques et Minières, Orléans, France

15:40

CFD and mass transfer in industrial gas-lift reactors for syngas fermentation

Lars Puiman, Delft University of Technology, The Netherlands

14:30

PAT for the assessment of population heterogeneity in scale up and down

Stefan Junne, TU Berlin, Germany

15:00

In-line application of Photon Density Wave spectroscopy as a PAT sensor in high-cell-density bioprocesses: Monitoring of E. coli growth and PHA formation in R. eutropha

Björn Gutschmann, TU Berlin, Germany & Thomas Schiewe, Physikalische Chemie Universität Potsdam / innoFSPEC, Germany

15:20

Design and development of electrochemical sensors for bioprocess monitoring

Aliyeh Hasanzadeh, Technical University of Denmark, Denmark

15:40

Control and optimization of polyhydroxyalkanoates production at pilot plant scale in real-time

Silvia Ochoa, Universidad de Antioquia, Colombia

16:30 - 20:00

Poster Session, Exhibition and Networking

17:00-18:00

Poster Discussions I+II

Poster 1-4 and 5-8

18:00-19:00

Poster Discussions III+IV

Poster 9-12 and 13-16

10:00

Welcome addresses and introduction

Peter Neubauer, TU Berlin, Germany

10:05

Plenary Talk: Systematic bioprocess devlopment in advanced microtiter plate and shake flask culture systems with online monitoring and feeding options

Jochen Büchs, RWTH Aachen, Germany

11:20

Exploiting Scale-down Tests for Engineering a Robust E. coli Host as a Platform for Industrial Production Processes

Ralf Takors, University of Stuttgart, Germany

11:50

Investigation of scale dependent factors in industrial human milk oligosaccharide production

Greta Gecse, DTU Bioengineering, Kgs. Lyngby, Denmark

12:10

Secretory protein producing Bacillus subtilis: Withstanding process inhomogeneities expected in a large-scale stirred tank bioreactor

Marco Oldiges, Forschungszentrum Jülich, Germany

11:20

Feedstock potential and valorisation of organic side-streams for value-added products

Saija Rasi, Natural Resources Institue Finland, Finland

11:50

Scale up from the cellar - the LX-Process as pretreatment for microbial conversion

Friedrich Streffer, LXP Group GmbH, Teltow, Germany

12:10

Upscaling butanol production using mixed microbial cultures

Tiago Pinto, Technical University of Denmark, Denmark

14:30

Potential of genome and proteome-reduced strains for protein and plasmid DNA production

Alvaro R. Lara, Universidad Autonoma Metropolitana-Cuajimalpa, Mexico

15:00

Scale-down of high cell density Fab production in E. coli

Florian Mayer, University of Natural Resources and Life Sciences, Vienna, Austria

15:20

N-1 perfusion-based IgG productions in stirred single-use bioreactors

Jan Müller, Zurich University of Applied Sciences, Switzerland

15:40

Evaluation of the clavulanic acid production integrating process simulation and systems biology

Rigoberto Rios Estepa, Universidad de Antioquia, Colombia

High-throughput single-cell-resolution microfluidics to accelerate microbial bioproduction bioprocess development

Arum Han, Texas A&M University, USA

15:00

Seperation of microalgae and polystyrene particles by dielectrophoresis

Danai Malti, TU Berlin, Germany

15:20

Dynamic microfluidic single-cell cultivation: Growth of Corynebacterium glutamicum at fluctuating environmental conditions

Sarah Täuber, Bielefeld University, Germany

15:40

Reproducing dynamic environment in microfluidic single-cell cultivation based on computational lifeline analysis

Phuong Ho, Forschungszentrum Jülich, Germany

16:30 - 20:00

Poster Session, Exhibition and Networking

17:00-18:00

Poster Discussions V+VI

Poster 17-20  and 21-24

18:00-19:00

Poster Discussions VII+VIII

Poster 25-28  and 29-32

10:00

Welcome addresses and introduction

Peter Neubauer, TU Berlin, Germany

10:05

Plenary Talk: Digitalization platform and supervisory control for continuous integrated manufacture of monoclonal antibodies

Massimo Morbidelli, Politecnico di Milano, Italy

11:20

Keynote Talk: Robot and machine learning assisted protein engineering on the high-throughput screening platform LARA

Mark Dörr, University Greifswald, Germany

11:50

Towards accelerated bioprocess development: Using cell-free protein synthesis to screen for promising biocatalysts

Katrin Rosenthal, TU Dortmund, Germany

12:10

Fed-batch like microtiter cultivations as high-throughput screening tool for E. coli production process development

Mathias Fink, University of Natural Resources and Life Sciences Vienna, Austria

11:20

Improvements for scalability of Lagrangian-Eulerian approaches for tracking lifelines of single cells in large bioreactors

Matthias Reuss, University of Stuttgart, Germany

11:50

Black box modelling approaches to judge a yeast extracts influence on microbial growth and production

Stefanie Kaul, Hamburg University of Applied Sciences, Germany

12:10

On the modelling of microbial population dynamics using partial differential equations

Jerome Morchain, Toulouse Biotechnology Institute, France

14:30

Keynote talk: Smart digital solutions for USP and DSP to master bioengineering challenges towards industry 4.0 in biopharma

Michael Sokolov, DataHow / ETH Zürich, Switzerland

15:00

Keynote talk: The CompuGene automated platform for the construction and characterization of genetic parts and microbial cell factories

Johannes Kabisch, TU Darmstadt, Germany

15:30

Modelling approaches with a fully-automated microbial fermentation platform

Vignesh Rajamanickam, Boehringer Ingelheim, Vienna, Austria

15:50

Towards an autonomous model based high throughput bioprocess development and clone discrimination

Sebastian Hans, TU Berlin, Germany

14:30

Process development of polyhydroxyalkanoate (PHA) bioplastics production from lipid based waste and raw materials

Sebastian L. Riedel, TU Berlin, Germany

15:00

Usage of mealworms to recover and purify polyhydroxyalkanoate granules from Cupriavidus necator cells

Kumar Sudesh, Universiti Sains Malaysia, Malaysia

15:30

Extraction of chitin from American lobster (Homarus americanus) shells and fabrication of membranes for potential biomedical use

Christopher Brigham, Wentworth Institute of Technology, USA

15:50

Low quality by-products for high quality products - Processing strategy and application development for the circular economy

Thomas Grimm, Animox GmbH, Germany

16:30

Plenary Talk:  Integrated and Networked Systems and Processes – A Perspective for Digital Transformation in (Bio) Process Engineering

Michael Maiwald, BAM

17:15

Closing Remarks / Best Poster & Presentation Award

Peter Neubauer, TU Berlin