The 9th BioProScale Symposium brought together a record almost 300 participants from academia and industry in Berlin to discuss the latest developments in bioprocess scale-up and scale-down, process analytics, modelling, and scalable cultivation. With 30 talks, 70 posters, a dedicated exhibition, and several awards for outstanding scientific contributions, the event once again highlighted the dynamic progress and strong community spirit in bioprocess engineering.

The 9th BioProScale, held from April 20 to 22 in Berlin, drew a record 300 participants from academia and industry. 30 talks and 70 posters presented recent developments in scaling up and down of bioprocesses, heterogeneities, upstream bioprocess development, process analytical technologies, and modelling. The plenary talks spotlighted trends in bioprocess design and opportunities for bioproducts in a changing market environment and under uncertainties in politics and policy, as well as new possibilities arising for bioprocess development and optimization supported by technological developments in other areas. The exhibition included many interesting company-driven new products and developments relevant to process analysis, bioreactor automation, scale-down studies, and scalable microbial cultivation.

During the conference, several contributors have been awarded:

Lifetime Achievement Award

Matthias Reuss, in recognition of his lifetime achievements

Best poster presentations:

1st place: Victor Puig I Laporda (Novo Nordisk Foundation Center for Biosustainability and DTU, Denmark) and co-authors, for the poster entitled: Real-time CFD: Emulating 3D bioreactor gradients in milliseconds

2nd place: Johannes T. Nicklisch (BHT and TU Berlin, Germany) and co-authors, for the poster entitled: Carbon-to-phosphorus ratio optimization for poly(hydroxybutyrate co-hydroxyhexanoate) production in high cell density cultivation under phosphorus limitation condition

3rd place: Maximilian Sehrt (University of Liège, Belgium) and his co-author, for the poster entitled: Uncovering a population-level safety mechanism for bioprocesses handling inhibiting substrates

Shared 3rd place: Sidharth Jaya Sankar (University of Stuttgart, Germany) and co-authors, for the poster entitled: Scale-down bioreactor studies on heterologous protein production in stringent response modulated E. coli chassis

Best talks of young scientists:

1st place: Luca Antonia Grebe (RWTH Aachen, Germany) and co-authors, for the talk: Smart feeding: Raman-based glucose control for enhanced malic acid fermentation

2nd place: Johan Le Nepvou de Carfort (DTU, Denmark) and co-authors, for the talk entitled: Using CFD-based compartment models to resolve spatial heterogeneities in industrial processes

3rd place: Simon Taeuber (TU Berlin, Germany) together with Anne Kathrine Clausen (Aalborg University, Denmark) and co-authors, for the talk entitled: Lipid production in Schizochytrium limacinum SR21 from biogenic residues

Shared 3rd place: Saskia Waldburger (TU Berlin, Germany) and co-authors, for the talk entitled: Integration of online HPLC analytics into chemostat-based polyhydroxyalkanoate production from dark fermentation effluent

We congratulate all winners! We also want to thank Bionet SA and Wiley for their support of the poster and talk awards!

The abstracts of all talks and posters are available in the abstract booklet.

Photos of the event are avaiable here.

The next BioProScale Symposium will take place in 2028.