The 6th BioProScale Symposium “Innovative scale-up and scale-down for bioprocess intensification” will take place from March 30 to April 1, 2020 in Berlin, Germany. The symposium is targeted at experts from research & development and industrial practice in bioprocessing of pharmaceuticals, food, feed and renewables.

Consistent development of new bioprocesses needs to be performed at the perspective of the final process scale. Therefore an efficient bioprocess development should consider large‑scale effects and integrate them from early stages onwards together with PAT and QbD. This includes technical challenges (sensors, modelling), the cellular dynamic regulatory networks and population dynamics. Current progresses in automation and parallelization demand for a higher degree of digitalization and advanced data treatment.

“Our aim is to discuss the efficiency of the whole product and process life cycle, from the raw materials and early screening stages until industrial-scale production and final application”, says Prof. Dr. Peter Neubauer, Head of Bioprocess Technology of Technische Universität Berlin and organiser of the symposium. The congress takes place at the Langenbeck-Virchow-Haus, a venerabel congress venue in the center of Berlin. The organizers looking forward to welcome around 300 attendees from all over the world.

The symposium topics include in particular:

Industrial-Scale Bioprocessing
Scale-down and scale-up approaches, industrial-scale operation, population heterogeneity, process monitoring and advanced control, modelling of industrial-scale processes, mixing and reactor characterization, process robustness and repeatability, integrated upstream and downstream operations

Process Analytical Technologies (PAT)
Multiparameter analysis, non-invasive sensors, single-cell based monitoring, soft sensors, fault identification and diagnosis, multiposition measurements, data handling and exploration, monitoring and control of co- and mixed cultures

High-Throughput Bioprocessing and Automation
Lab automation and robotics, automated screenings in bioprocess development, DoE, model‑based experimental designs, algorithm based operations and operational space characterisation, evolutionary strategies for strains and processes, communication trends for dynamic device operation and data flow, high-throughput strain engineering

Single-Use Bioreactors and Applications
Reactor types from µl to m³, sensors for single-use processes, continuous processing, scalability, sustainability, modular manufacturing, microbial and mammalian / plant cell cultures

Bioprocesses for a Circular Economy
Waste streams to value-added products, pretreatment, feedstock flexibility, scale-up / scale-down of biorefinery concepts, closed carbon cycles, smart bioproduction grids, decentralised production

Microsystems for Bioprocesses
Miniaturisation through microelectronics, physical sensors, biosensors, intelligent microwell plates, co-integration of microfluidics, lab-on-chip systems

A special session is dedicated at biotechnology in Latin America.

The 6th BioProScale Symposium is jointly organised by the Department of Bioprocess Engineering, Technische Universität Berlin, and the Institute for Gaerungsgewerbe und Biotechnologie zu Berlin (IfGB).

Congress venue: Langenbeck-Virchow-Haus, Luisenstr. 58/59, 10117 Berlin (Mitte), Germany

Congress language: English.

With accompanying exhibition.

More information and registration at www.bioproscale-conference.org